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Design of Potent and Controllable Anticoagulants Using DNA Aptamers and Nanostructures
The regulation of thrombin activity offers an opportunity to regulate blood clotting because of the central role played by this molecule in the coagulation cascade. Thrombin-binding DNA aptamers have been used to inhibit thrombin activity. In the past, to address the low efficacy reported for these...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273181/ https://www.ncbi.nlm.nih.gov/pubmed/26861277 http://dx.doi.org/10.3390/molecules21020202 |