Microwave-Assisted Synthesis of Novel Pyrazolo[3,4-g][1,8]naphthyridin-5-amine with Potential Antifungal and Antitumor Activity

The microwave assisted reaction between heterocyclic o-aminonitriles 1 and cyclic ketones 2 catalyzed by zinc chloride led to new series of pyrazolo[3,4-b][1,8]naphthyridin-5-amines 3 in good yields. This procedure provides several advantages such as being environmentally friendly, high yields, simp...

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Detalles Bibliográficos
Autores principales: Acosta, Paola, Butassi, Estefanía, Insuasty, Braulio, Ortiz, Alejandro, Abonia, Rodrigo, Zacchino, Susana A., Quiroga, Jairo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273193/
https://www.ncbi.nlm.nih.gov/pubmed/25985354
http://dx.doi.org/10.3390/molecules20058499

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273193/
https://www.ncbi.nlm.nih.gov/pubmed/25985354
http://dx.doi.org/10.3390/molecules20058499

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