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A Series of Oleanolic Acid Derivatives as Anti-Hepatitis B Virus Agents: Design, Synthesis, and in Vitro and in Vivo Biological Evaluation

A series of oleanolic acid derivatives were synthesized by diverse reactions, including the introduction of conjugated alkadiene and epoxy ring moieties formed by means of photosensitized oxidation. Eosin Y was used as photosensitizer during this process. Next the cytotoxicity of the products was ev...

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Detalles Bibliográficos
Autores principales: Yan, Wenqiang, Zhang, Chenze, Li, Bi, Xu, Xin, Liang, Miao, Gu, Shun, Chu, Fuhao, Xu, Bing, Ren, Jian, Wang, Penglong, Lei, Haimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273212/
https://www.ncbi.nlm.nih.gov/pubmed/27023498
http://dx.doi.org/10.3390/molecules21040402