Inhibitors of the Hydrolytic Enzyme Dimethylarginine Dimethylaminohydrolase (DDAH): Discovery, Synthesis and Development

Dimethylarginine dimethylaminohydrolase (DDAH) is a highly conserved hydrolytic enzyme found in numerous species, including bacteria, rodents, and humans. In humans, the DDAH-1 isoform is known to metabolize endogenous asymmetric dimethylarginine (ADMA) and monomethyl arginine (l-NMMA), with ADMA pr...

Descripción completa

Detalles Bibliográficos
Autores principales: Murphy, Rhys B., Tommasi, Sara, Lewis, Benjamin C., Mangoni, Arduino A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273216/
https://www.ncbi.nlm.nih.gov/pubmed/27187323
http://dx.doi.org/10.3390/molecules21050615

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273216/
https://www.ncbi.nlm.nih.gov/pubmed/27187323
http://dx.doi.org/10.3390/molecules21050615

Ejemplares similares