New Isoxazolidine-Conjugates of Quinazolinones—Synthesis, Antiviral and Cytostatic Activity

A novel series of (3-diethoxyphosphoryl)isoxazolidines substituted at C5 with various quinazolinones have been synthesized by the 1,3-dipolar cycloaddition of N-methyl-C-(diethoxyphosphoryl)nitrone with N3-substitued 2-vinyl-3H-quinazolin-4-ones. All isoxazolidines were assessed for antiviral activi...

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Detalles Bibliográficos
Autores principales: Piotrowska, Dorota G., Andrei, Graciela, Schols, Dominique, Snoeck, Robert, Grabkowska-Drużyc, Magdalena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273226/
https://www.ncbi.nlm.nih.gov/pubmed/27455228
http://dx.doi.org/10.3390/molecules21070959

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273226/
https://www.ncbi.nlm.nih.gov/pubmed/27455228
http://dx.doi.org/10.3390/molecules21070959

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