Novel Improved Synthesis of HSP70 Inhibitor, Pifithrin-μ. In Vitro Synergy Quantification of Pifithrin-μ Combined with Pt Drugs in Prostate and Colorectal Cancer Cells

We describe a novel improved approach to the synthesis of the important and well-known heat shock protein 70 inhibitor (HSP70), pifithrin-μ, with corresponding and previously unreported characterisation. The first example of a combination study comprising HSP70 inhibitor pifithrin-μ and cisplatin or...

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Detalles Bibliográficos
Autores principales: McKeon, Aoife M., Egan, Alan, Chandanshive, Jay, McMahon, Helena, Griffith, Darren M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273252/
https://www.ncbi.nlm.nih.gov/pubmed/27455212
http://dx.doi.org/10.3390/molecules21070949

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273252/
https://www.ncbi.nlm.nih.gov/pubmed/27455212
http://dx.doi.org/10.3390/molecules21070949

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