Graveoline Analogs Exhibiting Selective Acetylcholinesterase Inhibitory Activity as Potential Lead Compounds for the Treatment of Alzheimer’s Disease

This study designed and synthesized a series of new graveoline analogs on the basis of the structural characteristics of acetylcholinesterase (AChE) dual-site inhibitors. The activity of these analogs was also evaluated. Results showed that the synthesized graveoline analogs displayed stronger inhib...

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Detalles Bibliográficos
Autores principales: Li, Zeng, Mu, Chaoyu, Wang, Bin, Jin, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273267/
https://www.ncbi.nlm.nih.gov/pubmed/26805806
http://dx.doi.org/10.3390/molecules21020132

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273267/
https://www.ncbi.nlm.nih.gov/pubmed/26805806
http://dx.doi.org/10.3390/molecules21020132

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