Synthesis of Xylitan Derivatives and Preliminary Evaluation of in Vitro Trypanocidal Activity

A series of novel xylitan derivatives derived from xylitol were synthesized using operationally simple procedures. A xylitan acetonide was the key intermediate used to prepare benzoate, arylsulfonate esters and 1,2,3-triazole derivatives of xylitan. These compounds were evaluated for their in vitro...

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Detalles Bibliográficos
Autores principales: Elias, Paula Regina, Coelho, Gleicekelly Silva, Xavier, Viviane Flores, Sales Junior, Policarpo Ademar, Romanha, Alvaro José, Murta, Silvane Maria Fonseca, Carneiro, Claudia Martins, Camilo, Nilton Soares, Hilário, Flaviane Francisco, Taylor, Jason Guy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273285/
https://www.ncbi.nlm.nih.gov/pubmed/27735872
http://dx.doi.org/10.3390/molecules21101342

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273285/
https://www.ncbi.nlm.nih.gov/pubmed/27735872
http://dx.doi.org/10.3390/molecules21101342

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