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Efficient Double Suzuki Cross-Coupling Reactions of 2,5-Dibromo-3-hexylthiophene: Anti-Tumor, Haemolytic, Anti-Thrombolytic and Biofilm Inhibition Studies

The present study describes several novel 2,5-biaryl-3-hexylthiophene derivatives (3a–i) synthesized via a Pd(0)-catalyzed Suzuki cross-coupling reaction in moderate to good yields. The novel compounds were also analyzed for their anti-thrombolytic, haemolytic, and biofilm inhibition activities. In...

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Detalles Bibliográficos
Autores principales: Ikram, Hafiz Mansoor, Rasool, Nasir, Zubair, Muhammad, Khan, Khalid Mohammed, Abbas Chotana, Ghayoor, Akhtar, Muhammad Nadeem, Abu, Nadiah, Alitheen, Noorjahan Banu, Elgorban, Abdallah Mohamed, Rana, Usman Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273304/
https://www.ncbi.nlm.nih.gov/pubmed/27472312
http://dx.doi.org/10.3390/molecules21080977