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Synthesis and Biological Evaluation of Triazolyl 13α-Estrone–Nucleoside Bioconjugates
2′-Deoxynucleoside conjugates of 13α-estrone were synthesized by applying the copper-catalyzed alkyne–azide click reaction (CuAAC). For the introduction of the azido group the 5′-position of the nucleosides and a propargyl ether functional group on the 3-hydroxy group of 13α-estrone were chosen. The...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273310/ https://www.ncbi.nlm.nih.gov/pubmed/27626395 http://dx.doi.org/10.3390/molecules21091212 |