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Structure, Solubility and Stability of Orbifloxacin Crystal Forms: Hemihydrate versus Anhydrate

Orbifloxacin (ORBI) is a widely used antimicrobial drug of the fluoroquinolone class. In the official pharmaceutical compendia the existence of polymorphism in this active pharmaceutical ingredient (API) is reported. No crystal structure has been reported for this API and as described in the literat...

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Detalles Bibliográficos
Autores principales: Santos, Olimpia Maria Martins, Freitas, Jennifer Tavares Jacon, Cazedey, Edith Cristina Laignier, de Araújo, Magali Benjamim, Doriguetto, Antonio Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273335/
https://www.ncbi.nlm.nih.gov/pubmed/27005603
http://dx.doi.org/10.3390/molecules21030328