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Structure, Solubility and Stability of Orbifloxacin Crystal Forms: Hemihydrate versus Anhydrate
Orbifloxacin (ORBI) is a widely used antimicrobial drug of the fluoroquinolone class. In the official pharmaceutical compendia the existence of polymorphism in this active pharmaceutical ingredient (API) is reported. No crystal structure has been reported for this API and as described in the literat...
Autores principales: | Santos, Olimpia Maria Martins, Freitas, Jennifer Tavares Jacon, Cazedey, Edith Cristina Laignier, de Araújo, Magali Benjamim, Doriguetto, Antonio Carlos |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273335/ https://www.ncbi.nlm.nih.gov/pubmed/27005603 http://dx.doi.org/10.3390/molecules21030328 |
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