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Alpha- and Beta-Cyclodextrin Inclusion Complexes with 5-Fluorouracil: Characterization and Cytotoxic Activity Evaluation

Cyclodextrins are natural macrocyclic oligosaccharides able to form inclusion complexes with a wide variety of guests, affecting their physicochemical and pharmaceutical properties. In order to obtain an improvement of the bioavailability and solubility of 5-fluorouracil, a pyrimidine analogue used...

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Detalles Bibliográficos
Autores principales: Di Donato, Cristina, Lavorgna, Margherita, Fattorusso, Roberto, Isernia, Carla, Isidori, Marina, Malgieri, Gaetano, Piscitelli, Concetta, Russo, Chiara, Russo, Luigi, Iacovino, Rosa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273350/
https://www.ncbi.nlm.nih.gov/pubmed/27916966
http://dx.doi.org/10.3390/molecules21121644