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MASM, a Matrine Derivative, Offers Radioprotection by Modulating Lethal Total-Body Irradiation-Induced Multiple Signaling Pathways in Wistar Rats

Matrine is an alkaloid extracted from Sophora flavescens Ait and has many biological activities, such as anti-inflammatory, antitumor, anti-fibrosis, and immunosuppressive properties. In our previous studies, the matrine derivative MASM was synthesized and exhibited potent inhibitory activity agains...

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Detalles Bibliográficos
Autores principales: Li, Jianzhong, Xu, Jing, Lu, Yiming, Qiu, Lei, Xu, Weiheng, Lu, Bin, Hu, Zhenlin, Chu, Zhiyong, Chai, Yifeng, Zhang, Junping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273364/
https://www.ncbi.nlm.nih.gov/pubmed/27196884
http://dx.doi.org/10.3390/molecules21050649