Delivery of Gemcitabine Prodrugs Employing Mesoporous Silica Nanoparticles

In this paper, mesoporous silica nanoparticles (MSNs) were studied as vehicles for the delivery of the antitumoral drug gemcitabine (GEM) and of its 4-(N)-acyl derivatives, (4-(N)-valeroyl-(C5GEM), 4-(N)-lauroyl-(C12GEM) and 4-(N)-stearoyl-gemcitabine (C18GEM)). The loading of the GEM lipophilic pro...

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Detalles Bibliográficos
Autores principales: Malfanti, Alessio, Miletto, Ivana, Bottinelli, Emanuela, Zonari, Daniele, Blandino, Giulia, Berlier, Gloria, Arpicco, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273405/
https://www.ncbi.nlm.nih.gov/pubmed/27110750
http://dx.doi.org/10.3390/molecules21040522

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273405/
https://www.ncbi.nlm.nih.gov/pubmed/27110750
http://dx.doi.org/10.3390/molecules21040522

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