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New Approaches to the Role of Thrombin in Acute Coronary Syndromes: Quo Vadis Bivalirudin, a Direct Thrombin Inhibitor?

The pathophysiology of acute coronary syndrome (ACS) involves platelet activation and thrombus formation after the rupture of atherosclerotic plaques. Thrombin is generated at the blood-plaque interface in association with cellular membranes on cells and platelets. Thrombin also amplifies the respon...

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Detalles Bibliográficos
Autores principales: Esteve-Pastor, María Asunción, Hernández-Romero, Diana, Valdés, Mariano, Marín, Francisco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273416/
https://www.ncbi.nlm.nih.gov/pubmed/26927051
http://dx.doi.org/10.3390/molecules21030284