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Panax Notoginseng Saponins as a Novel Nature Stabilizer for Poorly Soluble Drug Nanocrystals: A Case Study with Baicalein

This study is aimed at seeking a nature saponin-based stabilizer for drug nanosuspensions. A poorly soluble drug (baicalein, BCL) was used as a model drug. BCL nanosuspensions with particle size of 156 nm were prepared by means of homogenization and converted into BCL nanocrystals (BCL-NC) stabilize...

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Detalles Bibliográficos
Autores principales: Xie, Yuanbiao, Ma, Yueqin, Xu, Junnan, Liu, Yang, Yue, Pengfei, Zheng, Qin, Hu, Pengyi, Yang, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273425/
https://www.ncbi.nlm.nih.gov/pubmed/27589712
http://dx.doi.org/10.3390/molecules21091149