Novel Selective Butyrylcholinesterase Inhibitors Incorporating Antioxidant Functionalities as Potential Bimodal Therapeutics for Alzheimer’s Disease

Isosorbide-2-carbamates-5-aryl esters are highly potent and very selective butyrylcholinesterase inhibitors. The objective of the present work was to address the hypothesis that the isosorbide-aryl-5-ester group could be replaced with an antioxidant functionality while maintaining inhibitor effects...

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Detalles Bibliográficos
Autores principales: Jones, Mike, Wang, Jun, Harmon, Shona, Kling, Beata, Heilmann, Jörg, Gilmer, John F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273432/
https://www.ncbi.nlm.nih.gov/pubmed/27534722
http://dx.doi.org/10.3390/molecules21040440

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273432/
https://www.ncbi.nlm.nih.gov/pubmed/27534722
http://dx.doi.org/10.3390/molecules21040440

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