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Novel Selective Butyrylcholinesterase Inhibitors Incorporating Antioxidant Functionalities as Potential Bimodal Therapeutics for Alzheimer’s Disease

Isosorbide-2-carbamates-5-aryl esters are highly potent and very selective butyrylcholinesterase inhibitors. The objective of the present work was to address the hypothesis that the isosorbide-aryl-5-ester group could be replaced with an antioxidant functionality while maintaining inhibitor effects...

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Detalles Bibliográficos
Autores principales:	Jones, Mike, Wang, Jun, Harmon, Shona, Kling, Beata, Heilmann, Jörg, Gilmer, John F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2016
Materias:	Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273432/ https://www.ncbi.nlm.nih.gov/pubmed/27534722 http://dx.doi.org/10.3390/molecules21040440

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