Design, Synthesis and Cytotoxicity of Novel Dihydroartemisinin-Coumarin Hybrids via Click Chemistry

In order to develop novel chemotherapeutic agents with potent anticancer activities, we designed four series of novel compounds employing hybridization strategy. Twenty novel dihydroartemisinin-coumarin hybrids, 10a–e, 11a–e, 12a–e, 13a–e, were synthesized via click chemistry in this study and their...

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Detalles Bibliográficos
Autores principales: Tian, Ye, Liang, Zhen, Xu, Hang, Mou, Yanhua, Guo, Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273433/
https://www.ncbi.nlm.nih.gov/pubmed/27294901
http://dx.doi.org/10.3390/molecules21060758

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273433/
https://www.ncbi.nlm.nih.gov/pubmed/27294901
http://dx.doi.org/10.3390/molecules21060758

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