Preliminary LC-MS Based Screening for Inhibitors of Plasmodium falciparum Thioredoxin Reductase (PfTrxR) among a Set of Antimalarials from the Malaria Box

Plasmodium falciparum thioredoxin reductase (PfTrxR) has been identified as a potential drug target to combat growing antimalarial drug resistance. Medicines for Malaria Venture (MMV) has pre-screened and identified a set of 400 antimalarial compounds called the Malaria Box. From those, we have eval...

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Detalles Bibliográficos
Autores principales: Tiwari, Neil K., Reynolds, Priscilla J., Calderón, Angela I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273446/
https://www.ncbi.nlm.nih.gov/pubmed/27043496
http://dx.doi.org/10.3390/molecules21040424

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273446/
https://www.ncbi.nlm.nih.gov/pubmed/27043496
http://dx.doi.org/10.3390/molecules21040424

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