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Synergistic Antipseudomonal Effects of Synthetic Peptide AMP38 and Carbapenems

The aim was to explore the antimicrobial activity of a synthetic peptide (AMP38) and its synergy with imipenem against imipenem-resistant Pseudomonas aeruginosa. The main mechanism of imipenem resistance is the loss or alteration of protein OprD. Time-kill and minimal biofilm eradication concentrati...

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Detalles Bibliográficos
Autores principales: Rudilla, Héctor, Fusté, Ester, Cajal, Yolanda, Rabanal, Francesc, Vinuesa, Teresa, Viñas, Miguel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273456/
https://www.ncbi.nlm.nih.gov/pubmed/27626405
http://dx.doi.org/10.3390/molecules21091223