Inhibitory Interactions of Aspalathus linearis (Rooibos) Extracts and Compounds, Aspalathin and Z-2-(β-d-Glucopyranosyloxy)-3-phenylpropenoic Acid, on Cytochromes Metabolizing Hypoglycemic and Hypolipidemic Drugs

Rooibos extract, due to its glucose and lipid lowering effects, has potential as a nutraceutical for improvement of metabolic dysfunction. Potential herb-drug interactions as a result of the use of natural products are of increasing concern. Cytochrome P450 enzymes, CYP2C8, CYP2C9, and CYP3A4, are i...

Descripción completa

Detalles Bibliográficos
Autores principales: Patel, Oelfah, Muller, Christo, Joubert, Elizabeth, Louw, Johan, Rosenkranz, Bernd, Awortwe, Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273468/
https://www.ncbi.nlm.nih.gov/pubmed/27845750
http://dx.doi.org/10.3390/molecules21111515

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273468/
https://www.ncbi.nlm.nih.gov/pubmed/27845750
http://dx.doi.org/10.3390/molecules21111515

Ejemplares similares