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Inhibitory Interactions of Aspalathus linearis (Rooibos) Extracts and Compounds, Aspalathin and Z-2-(β-d-Glucopyranosyloxy)-3-phenylpropenoic Acid, on Cytochromes Metabolizing Hypoglycemic and Hypolipidemic Drugs

Rooibos extract, due to its glucose and lipid lowering effects, has potential as a nutraceutical for improvement of metabolic dysfunction. Potential herb-drug interactions as a result of the use of natural products are of increasing concern. Cytochrome P450 enzymes, CYP2C8, CYP2C9, and CYP3A4, are i...

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Detalles Bibliográficos
Autores principales:	Patel, Oelfah, Muller, Christo, Joubert, Elizabeth, Louw, Johan, Rosenkranz, Bernd, Awortwe, Charles
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273468/ https://www.ncbi.nlm.nih.gov/pubmed/27845750 http://dx.doi.org/10.3390/molecules21111515

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