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Solid-Phase Synthesis of Amine/Carboxyl Substituted Prolines and Proline Homologues: Scope and Limitations

A solid-phase procedure is used to synthesize racemic peptidomimetics based on the fundamental peptide unit. The peptidomimetics are constructed around proline or proline homologues variably substituted at the amine and carbonyl sites. The procedure expands the diversity of substituted peptidomimeti...

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Detalles Bibliográficos
Autores principales: Zhou, Ziniu, Scott, William L., O’Donnell, Martin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273503/
https://www.ncbi.nlm.nih.gov/pubmed/26999079
http://dx.doi.org/10.3390/molecules21030350