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Design, Synthesis and Biological Evaluation of Benzohydrazide Derivatives Containing Dihydropyrazoles as Potential EGFR Kinase Inhibitors

A series of novel benzohydrazide derivatives containing dihydropyrazoles have been synthesized as potential epidermal growth factor receptor (EGFR) kinase inhibitors and their biological activities as potential antiproliferative agents have been evaluated. Among these compounds, compound H20 exhibit...

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Detalles Bibliográficos
Autores principales: Wang, Hai-Chao, Yan, Xiao-Qiang, Yan, Tian-Long, Li, Hong-Xia, Wang, Zhong-Chang, Zhu, Hai-Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273578/
https://www.ncbi.nlm.nih.gov/pubmed/27527130
http://dx.doi.org/10.3390/molecules21081012