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Design, Synthesis and Biological Evaluation of Benzohydrazide Derivatives Containing Dihydropyrazoles as Potential EGFR Kinase Inhibitors
A series of novel benzohydrazide derivatives containing dihydropyrazoles have been synthesized as potential epidermal growth factor receptor (EGFR) kinase inhibitors and their biological activities as potential antiproliferative agents have been evaluated. Among these compounds, compound H20 exhibit...
Autores principales: | Wang, Hai-Chao, Yan, Xiao-Qiang, Yan, Tian-Long, Li, Hong-Xia, Wang, Zhong-Chang, Zhu, Hai-Liang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273578/ https://www.ncbi.nlm.nih.gov/pubmed/27527130 http://dx.doi.org/10.3390/molecules21081012 |
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