Synthesis of Thiazolo[5,4-f]quinazolin-9(8H)-ones as Multi-Target Directed Ligands of Ser/Thr Kinases

A library of thirty novel thiazolo[5,4-f]quinazolin-9(8H)-one derivatives belonging to four series designated as 12, 13, 14 and 15 was efficiently prepared, helped by microwave-assisted technology when required. The efficient multistep synthesis of methyl 6-amino-2-cyano- benzo[d]thiazole-7-carboxyl...

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Detalles Bibliográficos
Autores principales: Hédou, Damien, Godeau, Julien, Loaëc, Nadège, Meijer, Laurent, Fruit, Corinne, Besson, Thierry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273584/
https://www.ncbi.nlm.nih.gov/pubmed/27144552
http://dx.doi.org/10.3390/molecules21050578

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273584/
https://www.ncbi.nlm.nih.gov/pubmed/27144552
http://dx.doi.org/10.3390/molecules21050578

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