Study of the Activity and Possible Mechanism of Action of a Reversible Inhibitor of Recombinant Human KAT-2: A Promising Lead in Neurodegenerative and Cognitive Disorders

Abnormal levels of kynurenic acid (KYNA) in the human brain are believed to be connected to several central nervous system (CNS) diseases, therefore compounds which affect the production of this crucial metabolite are of interest in CNS drug development. The majority of KYNA production is accounted...

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Detalles Bibliográficos
Autores principales: Nematollahi, Alireza, Sun, Guanchen, Jayawickrama, Gayan S., Hanrahan, Jane R., Church, W. Bret
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273595/
https://www.ncbi.nlm.nih.gov/pubmed/27367665
http://dx.doi.org/10.3390/molecules21070856

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273595/
https://www.ncbi.nlm.nih.gov/pubmed/27367665
http://dx.doi.org/10.3390/molecules21070856

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