The Prodrug Approach: A Successful Tool for Improving Drug Solubility

Prodrug design is a widely known molecular modification strategy that aims to optimize the physicochemical and pharmacological properties of drugs to improve their solubility and pharmacokinetic features and decrease their toxicity. A lack of solubility is one of the main obstacles to drug developme...

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Detalles Bibliográficos
Autores principales: Jornada, Daniela Hartmann, dos Santos Fernandes, Guilherme Felipe, Chiba, Diego Eidy, de Melo, Thais Regina Ferreira, dos Santos, Jean Leandro, Chung, Man Chin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273601/
https://www.ncbi.nlm.nih.gov/pubmed/26729077
http://dx.doi.org/10.3390/molecules21010042

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273601/
https://www.ncbi.nlm.nih.gov/pubmed/26729077
http://dx.doi.org/10.3390/molecules21010042

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