18α-Glycyrrhetinic Acid Induces Apoptosis of HL-60 Human Leukemia Cells through Caspases- and Mitochondria-Dependent Signaling Pathways

In this study we investigate the molecular mechanisms of caspases and mitochondria in the extrinsic and intrinsic signal apoptosis pathways in human leukemia HL-60 cells after in vitro exposure to 18α-glycyrrhetinic acid (18α-GA). Cells were exposed to 18α-GA at various concentrations for various ti...

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Detalles Bibliográficos
Autores principales: Huang, Yi-Chang, Kuo, Chao-Lin, Lu, Kung-Wen, Lin, Jen-Jyh, Yang, Jiun-Long, Wu, Rick Sai-Chuen, Wu, Ping-Ping, Chung, Jing-Gung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273602/
https://www.ncbi.nlm.nih.gov/pubmed/27376261
http://dx.doi.org/10.3390/molecules21070872

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273602/
https://www.ncbi.nlm.nih.gov/pubmed/27376261
http://dx.doi.org/10.3390/molecules21070872

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