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Novel N-Substituted 2-(2-(Adamantan-1-yl)-1H-Indol-3-yl)-2-Oxoacetamide Derivatives: Synthesis and Biological Evaluation

In this study, a series of novel N-substituted 2-(2-(adamantan-1-yl)-1H-indol-3-yl)-2-oxoacetamide derivatives were synthesized, and evaluated for their cytotoxicity in human cell lines including Hela (cervical cancer), MCF7 (breast cancer ) and HepG2 (liver cancer). Several compounds were found to...

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Detalles Bibliográficos
Autores principales: Hu, Hong-Yu, Yu, Xu-Dong, Wang, Fei, Lin, Chun-Rong, Zeng, Jin-Zhang, Qiu, Ying-Kun, Fang, Mei-Juan, Wu, Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273615/
https://www.ncbi.nlm.nih.gov/pubmed/27164070
http://dx.doi.org/10.3390/molecules21050530