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Effect of Phyllanthus amarus Extract on 5-Fluorouracil-Induced Perturbations in Ribonucleotide and Deoxyribonucleotide Pools in HepG2 Cell Line

The aim of this study was to investigate the antitumor activities of Phyllanthus amarus (PHA) and its potential of herb–drug interactions with 5-Fluorouracil (5-FU). Cell viability, ribonucleotides (RNs) and deoxyribonucleotides (dRNs) levels, cell cycle distribution, and expression of thymidylate s...

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Detalles Bibliográficos
Autores principales: Guo, Jian-Ru, Chen, Qian-Qian, Lam, Christopher Wai-Kei, Wang, Cai-Yun, Xu, Feng-Guo, Liu, Bu-Ming, Zhang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273671/
https://www.ncbi.nlm.nih.gov/pubmed/27657029
http://dx.doi.org/10.3390/molecules21091254