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Antitumor Effect of the Mannich Base(1,3-bis-((3-Hydroxynaphthalen-2-yl)phenylmethyl)urea) on Hepatocellular Carcinoma

The present study was designed to evaluate the antitumor effects of the synthetic Mannich base 1,3-bis-((3-hydroxynaphthalen-2-yl)phenylmethyl)urea (1,3-BPMU) against HEP-G2 hepatoma cells and diethylnitrosamine (DEN)-induced hepatocarcinoma (HCC) in albino rats. In vitro analysis results revealed t...

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Detalles Bibliográficos
Autores principales: Vedarethinam, Vadanasundari, Dhanaraj, Karthik, Ilavenil, Soundharrajan, Arasu, Mariadhas Valan, Choi, Ki Choon, Al-Dhabi, Naif Abdullah, Srisesharam, Srigopalram, Lee, Kyung Dong, Kim, Da Hye, Dhanapal, Tamilvenvendan, Sivanesan, Ravikumar, Choi, Han Sung, Kim, Young Ock
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273734/
https://www.ncbi.nlm.nih.gov/pubmed/27187346
http://dx.doi.org/10.3390/molecules21050632