Inhibition of Uterine Contractility by Thalidomide Analogs via Phosphodiesterase-4 Inhibition and Calcium Entry Blockade

Uterine relaxation is crucial during preterm labor. Phosphodiesterase-4 (PDE-4) inhibitors have been proposed as tocolytics. Some thalidomide analogs are PDE-4 inhibitors. The aim of this study was to assess the uterus-relaxant properties of two thalidomide analogs, methyl 3-(4-nitrophthalimido)-3-(...

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Detalles Bibliográficos
Autores principales: Fernández-Martínez, Eduardo, Ponce-Monter, Héctor, Soria-Jasso, Luis E., Ortiz, Mario I., Arias-Montaño, José-Antonio, Barragán-Ramírez, Guillermo, Mayén-García, Cynthia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273742/
https://www.ncbi.nlm.nih.gov/pubmed/27739411
http://dx.doi.org/10.3390/molecules21101332

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273742/
https://www.ncbi.nlm.nih.gov/pubmed/27739411
http://dx.doi.org/10.3390/molecules21101332

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