Probing Steroidal Substrate Specificity of Cytochrome P450 BM3 Variants

M01A82W, M11A82W and M01A82WS72I are three cytochrome P450 BM3 (CYP102A1) variants. They can catalyze the hydroxylation of testosterone (TES) and norethisterone at different positions, thereby making them promising biocatalysts for steroid hydroxylation. With the aim of obtaining more hydroxylated s...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Xing, Wang, Zhi-Biao, Wang, Ya-Nan, Kong, Jian-Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273762/
https://www.ncbi.nlm.nih.gov/pubmed/27294908
http://dx.doi.org/10.3390/molecules21060760

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273762/
https://www.ncbi.nlm.nih.gov/pubmed/27294908
http://dx.doi.org/10.3390/molecules21060760

Ejemplares similares