Synthesis and Biological Evaluation of Novel Aromatic Imide-Polyamine Conjugates

Three types of conjugates in which aromatic imide scaffolds were coupled to diverse amine/polyamine motifs were synthesized, and their antitumor activities were evaluated in vitro and in vivo. Results showed that the conjugate 11e of 1,8-naphthilimide with spermine had pronounced effects on inhibiti...

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Detalles Bibliográficos
Autores principales: Li, Ming, Wang, Yuxia, Zhang, Jianying, Xie, Songqiang, Wang, Chaojie, Wu, Yingliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273765/
https://www.ncbi.nlm.nih.gov/pubmed/27916902
http://dx.doi.org/10.3390/molecules21121637

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273765/
https://www.ncbi.nlm.nih.gov/pubmed/27916902
http://dx.doi.org/10.3390/molecules21121637

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