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Asiatic Acid Attenuates Myocardial Ischemia/Reperfusion Injury via Akt/GSK-3β/HIF-1α Signaling in Rat H9c2 Cardiomyocytes

Myocardial ischemic/reperfusion injury results from severe impairment of coronary blood supply and leads to irreversible cell death, with limited therapeutic possibilities. Asiatic acid is a pentacyclic triterpenoid derived from the tropical medicinal plant Centella asiatica and serves a variety of...

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Detalles Bibliográficos
Autores principales: Huang, Xiang, Zuo, Li, Lv, Yanni, Chen, Chuqiao, Yang, Yaqin, Xin, Hongbo, Li, Yunman, Qian, Yisong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273770/
https://www.ncbi.nlm.nih.gov/pubmed/27657024
http://dx.doi.org/10.3390/molecules21091248