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Antiproliferative Activity and Cellular Uptake of Evodiamine and Rutaecarpine Based on 3D Tumor Models

Evodiamine (EVO) and rutaecarpine (RUT) are promising anti-tumor drug candidates. The evaluation of the anti-proliferative activity and cellular uptake of EVO and RUT in 3D multicellular spheroids of cancer cells would better recapitulate the native situation and thus better reflect an in vivo respo...

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Detalles Bibliográficos
Autores principales: Guo, Hui, Liu, Dongmei, Gao, Bin, Zhang, Xiaohui, You, Minli, Ren, Hui, Zhang, Hongbo, Santos, Hélder A., Xu, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273785/
https://www.ncbi.nlm.nih.gov/pubmed/27455219
http://dx.doi.org/10.3390/molecules21070954