Synthesis of Isoxazole and 1,2,3-Triazole Isoindole Derivatives via Silver- and Copper-Catalyzed 1,3-Dipolar Cycloaddition Reactions †

The CuI- or Ag(2)CO(3)-catalyzed [3+2] cycloaddition of propargyl-substituted dihydroisoindolin-1-one (3) with arylnitrile oxides 1a–d (Ar = Ph, p-MeC(6)H(4), p-MeOC(6)H(4), p-ClC(6)H(4)) produces in good yields novel 3,5-disubstituted isoxazoles 4 of the ethyl-2-benzyl-3-oxo-1-((3-arylisoxazol-5yl)...

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Detalles Bibliográficos
Autores principales: Rammah, Mohamed Mehdi, Gati, Wafa, Mtiraoui, Hasan, Rammah, Mohamed El Baker, Ciamala, Kabula, Knorr, Michael, Rousselin, Yoann, Kubicki, Marek M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273791/
https://www.ncbi.nlm.nih.gov/pubmed/26959000
http://dx.doi.org/10.3390/molecules21030307

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273791/
https://www.ncbi.nlm.nih.gov/pubmed/26959000
http://dx.doi.org/10.3390/molecules21030307

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