Novel Radioligands for Cyclic Nucleotide Phosphodiesterase Imaging with Positron Emission Tomography: An Update on Developments Since 2012

Cyclic nucleotide phosphodiesterases (PDEs) are a class of intracellular enzymes that inactivate the secondary messenger molecules, cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP). Thus, PDEs regulate the signaling cascades mediated by these cyclic nucleotides and aff...

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Detalles Bibliográficos
Autores principales: Schröder, Susann, Wenzel, Barbara, Deuther-Conrad, Winnie, Scheunemann, Matthias, Brust, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273803/
https://www.ncbi.nlm.nih.gov/pubmed/27213312
http://dx.doi.org/10.3390/molecules21050650

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273803/
https://www.ncbi.nlm.nih.gov/pubmed/27213312
http://dx.doi.org/10.3390/molecules21050650

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