Identification of Selective ERRγ Inverse Agonists

GSK5182 (4) is currently one of the lead compounds for the development of estrogen-related receptor gamma (ERRγ) inverse agonists. Here, we report the design, synthesis, pharmacological and in vitro absorption, distribution, metabolism, excretion, toxicity (ADMET) properties of a series of compounds...

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Detalles Bibliográficos
Autores principales: Kim, Jina, Im, Chun Young, Yoo, Eun Kyung, Ma, Min Jung, Kim, Sang-Bum, Hong, Eunmi, Chin, Jungwook, Hwang, Hayoung, Lee, Sungwoo, Kim, Nam Doo, Jeon, Jae-Han, Lee, In-Kyu, Jeon, Yong Hyun, Choi, Hueng-Sik, Kim, Seong Heon, Cho, Sung Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273807/
https://www.ncbi.nlm.nih.gov/pubmed/26771593
http://dx.doi.org/10.3390/molecules21010080

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273807/
https://www.ncbi.nlm.nih.gov/pubmed/26771593
http://dx.doi.org/10.3390/molecules21010080

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