Hydrogen Bonding: Between Strengthening the Crystal Packing and Improving Solubility of Three Haloperidol Derivatives

The purpose of this study is to confirm the impact of polar functional groups on inter and intra-molecular hydrogen bonding in haloperidol (HP) and droperidol (DP) and, hence, their effects on dissolution using a new approach. To confirm our theory, a new molecule: deshydroxy-haloperidol (DHP) was d...

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Detalles Bibliográficos
Autores principales: Saluja, Hardeep, Mehanna, Ahmed, Panicucci, Riccardo, Atef, Eman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273816/
https://www.ncbi.nlm.nih.gov/pubmed/27258248
http://dx.doi.org/10.3390/molecules21060719

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273816/
https://www.ncbi.nlm.nih.gov/pubmed/27258248
http://dx.doi.org/10.3390/molecules21060719

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