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Synthesis and Antifungal Activity against Fusarium oxysporum of Some Brassinin Analogs Derived from l-tryptophan: A DFT/B3LYP Study on the Reaction Mechanism

An efficient methodology to obtain novel antifungal analogs of brassinin 1 is described. Starting from l-tryptophan 2, N,N′-dialkylthiourea 4, 4-[(1H-indol-3-yl)methylene]-2-sulfanylidene-1,3-thiazolidin-5-one 5 and alkyl (2S)-3-(1H-indol-3-yl)-2-{[(alkylsulfanyl)carbonothioyl]amino}propanoate 6 typ...

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Detalles Bibliográficos
Autores principales: Quiroga, Diego, Becerra, Lili Dahiana, Sadat-Bernal, John, Vargas, Nathalia, Coy-Barrera, Ericsson
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273850/
https://www.ncbi.nlm.nih.gov/pubmed/27727186
http://dx.doi.org/10.3390/molecules21101349