Cargando…

Synthesis and Determination of Physicochemical Properties of New 3-(4-Arylpiperazin-1-yl)-2-hydroxypropyl 4-Alkoxyethoxybenzoates

Nine new dihydrochloride salts of 3-(4-arylpiperazin-1-yl)-2-hydroxypropyl 4-alkoxyethoxybenzoates were designed and synthesized. The physicochemical properties such as lipophilicity index (log k(w)) and dissociation constant (pK(a)) were experimentally determined and compared to the software calcul...

Descripción completa

Detalles Bibliográficos
Autores principales: Marvanova, Pavlina, Padrtova, Tereza, Odehnalova, Klara, Hosik, Ondrej, Oravec, Michal, Mokry, Petr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273861/
https://www.ncbi.nlm.nih.gov/pubmed/27941622
http://dx.doi.org/10.3390/molecules21121682