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Synthesis and Determination of Physicochemical Properties of New 3-(4-Arylpiperazin-1-yl)-2-hydroxypropyl 4-Alkoxyethoxybenzoates

Nine new dihydrochloride salts of 3-(4-arylpiperazin-1-yl)-2-hydroxypropyl 4-alkoxyethoxybenzoates were designed and synthesized. The physicochemical properties such as lipophilicity index (log k(w)) and dissociation constant (pK(a)) were experimentally determined and compared to the software calcul...

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Detalles Bibliográficos
Autores principales:	Marvanova, Pavlina, Padrtova, Tereza, Odehnalova, Klara, Hosik, Ondrej, Oravec, Michal, Mokry, Petr
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2016
Materias:	Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273861/ https://www.ncbi.nlm.nih.gov/pubmed/27941622 http://dx.doi.org/10.3390/molecules21121682

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