Boronic Acid Group: A Cumbersome False Negative Case in the Process of Drug Design

Herein we present, an exhaustive docking analysis considering the case of autotaxin (ATX). HA155, a small molecule inhibitor of ATX, is co-crystallized. In order to further extract conclusions on the nature of the bond formed between the ligands and the amino acid residues of the active site, densit...

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Detalles Bibliográficos
Autores principales: Katsamakas, Sotirios, Papadopoulos, Anastasios G., Hadjipavlou-Litina, Dimitra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273881/
https://www.ncbi.nlm.nih.gov/pubmed/27617984
http://dx.doi.org/10.3390/molecules21091185

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273881/
https://www.ncbi.nlm.nih.gov/pubmed/27617984
http://dx.doi.org/10.3390/molecules21091185

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