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Identification and Characterisation of the Antimicrobial Peptide, Phylloseptin-PT, from the Skin Secretion of Phyllomedusa tarsius, and Comparison of Activity with Designed, Cationicity-Enhanced Analogues and Diastereomers

Antimicrobial peptides belonging to the phylloseptin family are mainly found in phyllomedusine frogs. These peptides not only possess potent antimicrobial activity but exhibit low toxicity against eukaryotic cells. Therefore, they are considered as promising drug candidates for a number of diseases....

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Detalles Bibliográficos
Autores principales: Gao, Yitian, Wu, Di, Xi, Xinping, Wu, Yue, Ma, Chengbang, Zhou, Mei, Wang, Lei, Yang, Mu, Chen, Tianbao, Shaw, Chris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273899/
https://www.ncbi.nlm.nih.gov/pubmed/27918477
http://dx.doi.org/10.3390/molecules21121667