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Synthesis and Evaluation of New 1,3,4-Thiadiazole Derivatives as Antinociceptive Agents
In the current work, new 1,3,4-thiadiazole derivatives were synthesized and investigated for their antinociceptive effects on nociceptive pathways of nervous system. The effects of these compounds against mechanical, thermal and chemical stimuli were evaluated by tail-clip, hot-plate and acetic acid...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273905/ https://www.ncbi.nlm.nih.gov/pubmed/27490523 http://dx.doi.org/10.3390/molecules21081004 |