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Synthesis and Evaluation of New 1,3,4-Thiadiazole Derivatives as Antinociceptive Agents

In the current work, new 1,3,4-thiadiazole derivatives were synthesized and investigated for their antinociceptive effects on nociceptive pathways of nervous system. The effects of these compounds against mechanical, thermal and chemical stimuli were evaluated by tail-clip, hot-plate and acetic acid...

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Detalles Bibliográficos
Autores principales: Altıntop, Mehlika Dilek, Can, Özgür Devrim, Demir Özkay, Ümide, Kaplancıklı, Zafer Asım
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273905/
https://www.ncbi.nlm.nih.gov/pubmed/27490523
http://dx.doi.org/10.3390/molecules21081004