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Evaluation of the Antidepressant Activity, Hepatotoxicity and Blood Brain Barrier Permeability of Methyl Genipin

Geniposide (GE) is the main bioactive component of Gardeniae Fructus. The hepatotoxicity of geniposide limited clinical application. In order to get a new geniposide derivative that has less hepatotoxicity and still possesses the antidepressant activity, a new C-1 hydroxyl methylation derivative nam...

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Detalles Bibliográficos
Autores principales: Che, Xin, Wang, Meiyu, Wang, Tian, Fan, Huaying, Yang, Mingyan, Wang, Wenyan, Xu, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273916/
https://www.ncbi.nlm.nih.gov/pubmed/27438811
http://dx.doi.org/10.3390/molecules21070923